In William Shakespeare’s Macbeth, Macduff asks the Porter, “What three things does drink especially provoke?” The Porter replies, “nose painting, sleep, and urine”—the first of which is usually taken to mean the red flush that comes across a drinker’s face. It also leads to lechery, the Porter says, adding, “it provokes the desire, but it takes away the performance.”

“Bomb the shit out of them!” was reportedly a drunken President Richard Nixon’s conclusion as to what should be done about Cambodia. Henry Kissinger recalled in an interview in 1999 that “two glasses of wine were quite enough to make him boisterous, just one more to grow bellicose or sentimental with slurred speech.”