The questions “Have you ever used Derbisol?” and “How often?” sometimes appear along with questions about alcohol, cocaine, and marijuana use on youth-risk surveys for students. Derbisol is a fictitious drug devised to test the reliability of the responder. In one survey, 163 of 894 students said that they had tried Derbisol—or 18.2 percent.

In the United States around 1787—the year that Thomas Jefferson took a three-month sabbatical to tour the vineyards of France and Italy—the average drinking American consumed the equivalent of an estimated six gallons of pure alcohol per year. The figure today is 2.2.