Primo Levi wrote that at Auschwitz “a large amount of alcohol was put at the disposal of” members of the Special Squad, inmates of the concentration camp who were forced to work the crematoriums, “and that they were in a permanent state of complete debasement and prostration.” One such inmate said, “Doing this work, one either goes crazy the first day or gets accustomed to it.”

Isolated from opium by the German chemist F. W. A. Sertürner around 1804, morphine (named after Morpheus, the Greek god of sleep and dreams) was used to treat opium addicts. Invented by Bayer Pharmaceuticals in 1898, heroin (derived from the Greek word for hero) was used to treat morphine addicts.